Synthesis of New N-Phthalimide Substituted Tricyclic Imide Containing Isoxazoline and Bispiro Functional Group as Possible Anti-cancer Agents

Authors : Omer Tahir GUNKARA, Nuket OCAL

Pages : 73-84

Doi:10.18596/jotcsa.338218

View : 17 | Download : 15

Publication Date : 2017-09-01

Article Type : Research Paper

Abstract :[3+2]-Cycloaddition reactions of N- phthalimide substituted tricyclic imide were studied to synthesize their isoxazoline and bispiro derivatives in excellent yields. All new synthesized compounds have been characterized by their FTIR, 1 H NMR, 13 C NMR, GC/MS and LC/MS insert ignore into journalissuearticles values(HRMS); analyses.
Keywords : Azomethine ylide, Bispiromolecules, Isoxazolines, Tetracyclic imides 3 2, Cycloaddition reaction