Eco-friendly Synthesis of Quinoxaline Derivatives Using Mineral Fertilizers as Heterogeneous Catalysts

Authors : Badr MALEK, İmane BAHAMMOU, Omar ZIMOU, Achraf EL HALLAOUI, Rachida GHAILANE, Said BOUKHRİS, Abdelaziz SOUIZI

Pages : 427-440

Doi:10.18596/jotcsa.577101

View : 20 | Download : 8

Publication Date : 2020-06-23

Article Type : Research Paper

Abstract :The synthesis of quinoxaline derivatives were heterogeneously catalyzed by phosphate-based catalyst fertilizers, MAP, DAP, or TSP. The reaction affords the desired products in excellent yields at ambient temperature. A series of studies were conducted to investigate the effect of solvent reaction, its volume, and catalyst amount. A study of the recyclability of catalysts removed from the reaction mixture by simple filtration was also carried out to find that the three phosphate-based catalysts retain their catalytic activities up to six cycles.
Keywords : Phosphate, Fertilizers, MAP, DAP, TSP, Quinoxaline