DETERMINATION of SOME ANTIOXIDANT ACTIVITIES and OXIDATIVE STRESS LEVES in PATIENTS with LIP and ORAL CAVITY CANCER

Authors : Ali Hussein MER, Halil ÖZKOL, Halit DEMİR, Şeyda BELLİ, Canan DEMİR, Ali ASLAN

Pages : 49-56

View : 42 | Download : 8

Publication Date : 2022-12-31

Article Type : Review Paper

Abstract :Squamous cell carcinomas constitute the majority of oral cavity tumors. Poor oral hygiene, smoking, chronic irritation and alcohol consumption are counted as etiological factors. In study, it was aimed to determine oxidative stress levels and some antioxidant activities such as superoxide dismutase insert ignore into journalissuearticles values(SOD);, reduced glutathione insert ignore into journalissuearticles values(GSH); and catalase insert ignore into journalissuearticles values(CAT); in cancer of the lip and oral cavity. Malondialdehyde insert ignore into journalissuearticles values(MDA); levels, SOD, GSH and CAT activities were measured using the spectrophotometric method. The results showed that SOD, CAT and GSH levels decreased significantly in the patient group insert ignore into journalissuearticles values(p<0.05);, while MDA levels increased significantly insert ignore into journalissuearticles values(p<0.05);. Lack of antioxidants can increase the development of oral and lip cancers.
Keywords : Lip and oral cavity cancers, SOD, GSH, CAT, MDA

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