Determination of Toxic Effect of Gamma Cyhalothrin in Dreissena polymorpha by Some Biomarkers

Authors : Ayşe Nur Aydın, Osman Serdar, Tuba Parlak Ak

Pages : 20-32

Doi:10.17216/limnofish.1556682

View : 90 | Download : 572

Publication Date : 2025-04-30

Article Type : Research Paper

Abstract :In this study, the effects of pesticides on the freshwater mussel Dreissena polymorpha, a non-target organism, were aimed to be determined through biochemical responses. For this purpose, first, the acute toxicity value (LC50) of Gamma Cyhalothrin (GCH) pesticide on D. polymorpha was determined by standard static method and the LC50 value was calculated as 13.64 mg/L using probit analysis. Then, superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) activities, malondialdehyde (MDA) and glutathione (GSH) level responses of D. polymorpha organism exposed to GCH sublethal concentrations for 24 and 96 hours were determined. In addition to biochemical biomarkers, histopathological responses were evaluated. In conclusion, this study demonstrated the abilities of GCH pesticides to induce oxidative stress. Moreover, MDA, GSH levels, SOD, CAT, GPx activities and histopathological responses could be used as an effective biomarker in D. polymorpha.
Keywords : Dreissena polymorpha, gamma cyhalothrin, biyobelirteç, oksidatif stres, histoloji

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