Serum amyloid A, haptoglobin and ceruloplasmin levels before and after treatment in cattle with dermatophytosis

Authors : Neslihan ŞELİMAN, Erdoğan UZLU, Ali Haydar KIRMIZIGÜL

Pages : 9-15

Doi:10.31797/vetbio.1241882

View : 41 | Download : 10

Publication Date : 2023-04-30

Article Type : Research Paper

Abstract :The aim of this study is to determine the changes in serum amyloid A insert ignore into journalissuearticles values(SAA);, haptoglobin insert ignore into journalissuearticles values(Hp); and ceruloplasmin insert ignore into journalissuearticles values(Cp); levels before and after treatment in cattle with dermatophytosis. The animal material of the study consisted of a total of 30 cattle, 20 with dermatophytosis and 10 healthy, of different ages and genders. Blood was taken from the sick animals twice, before and after the treatment, and once from the healthy animals, and their serum was separated. The obtained sera were stored at -20 ºC until the Hp, SAA and Cp levels were measured. Trichoben® insert ignore into journalissuearticles values(Interhas, TR); vaccine was administered to the sick animals twice, 14 days apart. When the pre-treatment and post-treatment serum Hp, SAA and Cp values of the sick animals were statistically compared, it was determined that the pre-treatment values were significantly higher insert ignore into journalissuearticles values(P<0.001); than the post-treatment values. Similarly, when the values of pre-treatment and control animals were compared, it was seen that the difference was significant insert ignore into journalissuearticles values(P<0.001);. When the serum SAA, Hp and Cp values of the animals in the post-treatment and control groups were compared, it was determined that the difference was statistically insignificant insert ignore into journalissuearticles values(P>0.05);. As a result, it was determined that SAA, Hp and Cp values, which are positive acute phase proteins, increased significantly in cattle with dermatophytosis and these values decreased with treatment. According to this result, it was concluded that serum SAA, Hp and Cp values are important biomarkers in the evaluation of the prognosis of the disease in cattle with dermatophytosis.
Keywords : Bovine, dermatophytosis, ceruloplasmin, haptoglobin, serum amyloid A

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