Relationship Between Autonomic Nervous System Activity and Recurrence After Cryoballoon Ablation in Patients with Paroxysmal Atrial Fibrillation

Authors : Filiz KIZILIRMAK YILMAZ, Fatih YILMAZ, Arzu YILDIRIM, Hacı Murat GÜNEŞ, Tayyar GÖKDENİZ, Fatih Erkam OLGUN, Tuğba AKTEMUR, Ümeyir SAVUR, Fethi KILIÇASLAN

Pages : 85-94

View : 25 | Download : 6

Publication Date : 2022-04-18

Article Type : Research Paper

Abstract :Introduction: In this study, we aimed to investigate the relationship between autonomic dysfunction insert ignore into journalissuearticles values(AD); determined according to the blood pressure insert ignore into journalissuearticles values(BP); and heart rate insert ignore into journalissuearticles values(HR); response in exercise treadmill test insert ignore into journalissuearticles values(ETT); prior to cryoballoon ablation insert ignore into journalissuearticles values(CBA);, and the recurrence of atrial fibrillation insert ignore into journalissuearticles values(AF); after CBA in patients with paroxysmal AF. Patients and Methods: Seventy-six patients insert ignore into journalissuearticles values(mean age 53 ± 11 years, 61.8% male); with paroxysmal AF who underwent CBA were enrolled. Before CBA the ETT was performed by all patients. BP and HR responses in ETT were compared between patients with and without AF recurrence. Results: AD rate was significantly higher in the group with recurrence compared to the non-recurrent group insert ignore into journalissuearticles values(p 0.05 for all);. Examining AD parameters, systolic blood pressure at peak exercise insert ignore into journalissuearticles values(SBPpeak); insert ignore into journalissuearticles values(p< 0.001); and diastolic blood pressure at peak exercise insert ignore into journalissuearticles values(DBPpeak); insert ignore into journalissuearticles values(p< 0.001);, slow heart rate recovery insert ignore into journalissuearticles values(HRR); insert ignore into journalissuearticles values(p< 0.001); were significantly higher in the recurrent group. Conclusion: AD may be associated with AF recurrence after CBA in patients with paroxysmal AF. SBPpeak, DBPpeak, and slow HRR appear to be predictors of AF recurrence after ablation.
Keywords : Atrial fibrillation, autonomic nervous system, catheter ablation