Production of antibacterial polyvinylpyrrolidone nanofibers containing silver nanoparticles via electrospinning method

Authors : Hava ÇAVUŞOĞLU VATANSEVER, Ayşegül ERSOY MERİÇBOYU

Pages : 13-23

View : 16 | Download : 9

Publication Date : 2019-06-18

Article Type : Research Paper

Abstract :Since polymeric nanofibers find extensive usage in medical applications, the risks associated with bacterial contamination must be taken into account. In this study, the production of antibacterial polyvinylpyrrolidone insert ignore into journalissuearticles values(PVP); nanofibers containing silver nanoparticles insert ignore into journalissuearticles values(AgNPs); was achieved. For this production AgNPs with the average diameters ranging from 5.69 nm to 14.83 nm were synthesized and characterized firstly. The properties of the nanofibers produced via electrospinning method were investigated by means of scanning electron microscopy insert ignore into journalissuearticles values(SEM); and X-ray diffraction insert ignore into journalissuearticles values(XRD); techniques. The effect of AgNPs on the conductivity of electrospinning solutions were investigated. The stability of nanofiber mats were determined to show the crosslinking efficiency. Finally, antimicrobial tests against three types of microorganisms insert ignore into journalissuearticles values( E. coli , S. aureus and A. niger ); were carried out according to zone of inhibition method. Antimicrobial test results proved that nanofibers containing AgNPs show inhibition against E.coli and S. aureus , while neat nanofibers not. Additionally, any antifungal activity was not observed against A. niger .
Keywords : Silver nanoparticles, polyvinylpyrrolidone, electrospinning, nanofibers