Effects of nickel sulphate on rat testes seminiferous tubules: An ultrastructural investigation

Authors : E Yenilmez, S Arbak, T Erbengi

Pages : 166-170

View : 17 | Download : 9

Publication Date : 1994-11-01

Article Type : Research Paper

Abstract :This study investigated the ultrastructural effects of daily oral doses of nickel sulphate insert ignore into journalissuearticles values(NiS04); insert ignore into journalissuearticles values(12.5 mg/kg); on rat testis seminiferous tubules on days 15, 60 and 95 of the experiment. The latter constituted the recovery group. The seminiferous tubules were severely damaged on the 15th and 60th days. The major findings were the germ cell sloughing and decreased spermatogenesis. A disorder in germ cell alignment was evident. Sertoli cell`s phagocytic activity was increased. Recovery which was aimed to be established on the 95th day following a 60 day- NiSC>4 administration could not be observed at the seminiferous tubules of that group.
Keywords : Testis, Nickel sulphate, Electronmicroscopy