Stress ulcer: A morphological approach

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Marmara Medical Journal
Volume:7 Issue:4
Stress ulcer: A morphological approach

Stress ulcer: A morphological approach

Authors : S ARBAK, F ŞEN, F ERCAN, İ ALİCAN, İ ALİCAN, N ASLAN, Bç YEĞEN

Pages : 178-186

View : 10 | Download : 11

Publication Date : 1994-11-01

Article Type : Research Paper

Abstract :The effects of starvation and cold-restraint stress on the rat stomach mucosa were investigated. Mucosal damage was evaluated using light, transmission insert ignore into journalissuearticles values(TEM); and scanning insert ignore into journalissuearticles values(SEM); electronmicroscopy. Light microscopy revealed hemorrhagic areas as well as cellular damage in the mucosa. At TEM level, severe degenerative changes were especially observed at parietal cells and chief cells of the fundic mucosa. SEM demonstrated a totally necrotic appearance of the mucosa at the ulcer region with widened gastric pits devoid of lining epithelium. We conclude that experimental stress conditions produce severe gastric mocosal damage.
Keywords : Stress ulcer, Gastric mucosa, Morphology

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