The use of gnrh agonists in the treatment of endometriomas with or without drainage

Authors : A Haberal, H Çelikkanat, M Uğur, G Özakşit, N Çiçek, P Moröy, S Batıoğlu

Pages : 175-178

View : 10 | Download : 12

Publication Date : 1995-10-01

Article Type : Research Paper

Abstract :In order to assess the effectiveness of GnRH-agonist insert ignore into journalissuearticles values(GnRH-a); therapy in the treatment of endometriomas, with or without surgical intervention, 26 women with laparoscopically proven endometriomas, greater than 3 cm diameter were recruited to the study. Fourteen women who had 19 endometriomas insert ignore into journalissuearticles values(5 of them were bilaterally);, had drainage of endometrioma at the initial laparoscopy. After the procedure, they had ovarian suppression with GnRH-a therapy for 6 months. The second group which consisted of 12 women, had 17 endometriomas. No surgical procedure was performed. They received only GnRH-A therapy for 6 months. At the second -look laparoscopy, the rates of decrease in ovarian AFS scores of endometriomas and complete resolution were found as 100% and 36.8% respectively, in the first group, In the second group the response was only 17.6% insert ignore into journalissuearticles values(p<0.0001);. In this prospective study we found that drainage of the cyst insert ignore into journalissuearticles values(surgical therapy); combined with the postoperative GnRH-a suppression is a better treatment modality for endometriomas. Than the use of GnRH-a insert ignore into journalissuearticles values(medical therapy); alone.
Keywords : GnRH agonist, endometriosis, endometrioma, laparoscopic surgery