Factor viii related antigen level in henoch - schonlein purpura

Authors : L Sever, S Çalışkan, F Akalın, N Hekim, H Özdoğan, N Arısoy, H Yazıcı

Pages : 121-123

View : 75 | Download : 9

Publication Date : 1996-06-01

Article Type : Research Paper

Abstract :Objective: It is a known fact that FVIII related antigen insert ignore into journalissuearticles values(FVIII Rag); level is raised in systemic necrotizing and large vessel vasculitis but contradictory results exist in small vessel vasculitis. We therefore assessed the value of this parameter in children with Henoch- Shonlein Purpura insert ignore into journalissuearticles values(HSP);. Methods: FVIII Rag, C-reactive protein insert ignore into journalissuearticles values(CRP); and erythrocyte sedimentation rate insert ignore into journalissuearticles values(ESR); were determined in 14 children with HSP. Control groups consisted of 6 children with juvenile rheumatoid arthritis insert ignore into journalissuearticles values(JRA);, 3 children with systemic necrotizing vasculitis and 8 normal children. Results: FVIII Rag levels were significantly higher in children with HSP compared to JRA and normal controls and these levels did not correlate with either ESR or CRP levels. Conclusion: It can be suggested that FVIII Rag level can be used as a marker for vasculitis, irrespective of vessel size.
Keywords : Henoch Schonlein Purpura, Factor VIII related antigen

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