Activated protein c resistance in myocardial infarction

Authors : B S Cebeci, B Y Cingözbay, A Öztürk, M Coşkun, N Üskent

Pages : 84-86

View : 15 | Download : 8

Publication Date : 1997-03-01

Article Type : Research Paper

Abstract :Objective: The aim of this study is to investigate the role of activated protein C resistance insert ignore into journalissuearticles values(APCR); as a contributing factor in the pathogenesis of myocardial infarction. Methods: Forty patients with acute myocardial infarction insert ignore into journalissuearticles values(AMI); who have been followed by the Cardiology Department of Gülhane Military Medical Academy Haydarpaşa Training Hospital and 30 healthy individuals were included in this study. Patient group consisted of 27 males and 13 females, insert ignore into journalissuearticles values(mean age 47.9 insert ignore into journalissuearticles values(23-81); control group composed of 16 males and 14 females, insert ignore into journalissuearticles values(mean age 46.1 insert ignore into journalissuearticles values(24-63); Whole blood count and routine biochemical work up were performed and activated protein C resistance insert ignore into journalissuearticles values(APCR); ratio, and activated partial thromboplastin time were evaluated in both groups. Results: Two patients and three controls had APCR. Mean APCR ratio was 2.56 ± 0.56 in the control and 2.74 ± 0.67 in the patient group and there was no statistically significant difference between the two groups insert ignore into journalissuearticles values(p>0.05);. Conclusion: Although APCR is a major risk factor for venous thrombosis, its role
Keywords : Activated protein C resistance, Acute myocardial infarction