- Marmara Medical Journal
- Special Issue:1: Oncology Special Issue
- Advances in the management of esophageal cancer
Advances in the management of esophageal cancer
Authors : Bruce D MINSKY
Pages : 3-10
Doi:10.5472/mmj.10059
View : 13 | Download : 9
Publication Date : 2015-09-30
Article Type : Research Paper
Abstract :The management of clinical stage III and IVa esophageal cancer has evolved in the past 2 decades. Based on the Cross trial, neoadjuvant chemoradiation, followed by surgical resection has become standard. For medically inoperable, definitive chemoradiation is most commonly used. The standard radiation dose is 50.4 Gy although trials of doseescalation are ongoing. At the current time, there are no definitive biomarkers to predict response. Keywords: Esophageal cancer, Radiation therapy, Chemotherapy, Dose-escalationKeywords : Esophageal cancer, Radiation therapy, Chemotherapy, Dose escalation