Effect of troponin I and coagulation parameters on mortality in COVID-19 patients

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Marmara Medical Journal
Volume:36 Issue:1
Effect of troponin I and coagulation parameters on mortality in COVID-19 patients

Effect of troponin I and coagulation parameters on mortality in COVID-19 patients

Authors : Meral DAG, Nilufer BULUT, M Cagatay TASKAPAN

Pages : 135-139

Doi:10.5472/marumj.1235703

View : 23 | Download : 8

Publication Date : 2023-01-31

Article Type : Research Paper

Abstract :Objective: Our aim is to determine the levels of troponin-I and some coagulation markers insert ignore into journalissuearticles values(D-dimer, fibrinogen and International Normalized Ratio insert ignore into journalissuearticles values(INR);); in coronavirus disease 2019 insert ignore into journalissuearticles values(COVID-19); patients and to investigate the effects of these markers on mortality. Patients and Methods: It is planned as a descriptive, cross-sectional and analytical study. The study was conducted by retrospectively scanning the files of COVID-19 patients who applied to Inonu University Turgut Ozal Medical Center between 01.03.2020 and 31.12.2020. Levels of cardiac troponin I markers and coagulation parameters insert ignore into journalissuearticles values(D-dimer, fibrinogen and INR); were detected. Results: The results of a total of 1858 patients were obtained. One thousand, three hundred and twenty-six patients with only troponin I and D-dimer results insert ignore into journalissuearticles values(Group 1);, 606 patients with only troponin I and fibrinogen results insert ignore into journalissuearticles values(Group 2);, and 1308 patients with only troponin I and INR results insert ignore into journalissuearticles values(Group 3); were included. Troponin I levels were significantly higher in all patients who died. 96.6% of the patients with high D-dimer levels died in Group 1, 85.5% of the patients with high fibrinogen levels died in Group 2 and 77.3 % of the patients with high INR levels died in Group 3. Conclusion: Measurements of troponin-I and coagulation markers such as D-dimer, fibrinogen and INR can help predict clinical severity and mortality in COVID-19 patients.
Keywords : COVID 19, Troponin I, Coagulation markers, D dimer, Fibrinogen, International Normalized Ratio

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