Identification of Some Chemical Constituents of the Leaves of Alstonia boonei and Bridelia ferruginea

Authors : Oluwatoyin Adenike FABİYİ, Olubunmi ATOLANİ, Gabriel A OLATUNJİ

Pages : 21-28

View : 582 | Download : 272

Publication Date : 2016-12-13

Article Type : Research Paper

Abstract :This study aims to investigate the phytochemical composition of the leaves of Alstonia boonei and Bridelia ferruginea. The leaves of the two plants were extracted successively with n-hexane and ethyl acetate, concentrated and fractionated over gravity silica gel column chromatography. Some fractions obtained were analyzed using gas chromatography mass spectroscopy insert ignore into journalissuearticles values(GC-MS);.  GC-MS results indicated that the main constituents of the fractions from Alstonia boonei were fatty acid methyl esters, while the main constituents of the fractions from Bridelia ferruginea were fatty acid esters insert ignore into journalissuearticles values(47.46%); and triterpenoids insert ignore into journalissuearticles values(43.39%);. Each of the fractions has at least one exclusive tetracyclic or pentacyclic triterpenoid present. Friedelan-3-one and clionasterol were present in the Alstonia boonei fractions, while beta-amyrin, lup-20insert ignore into journalissuearticles values(29);-en-3-one, lupeol, alpha-amyrin acetate and 4,4,6a,6b,8a,11,11,14b-octamethyl-1,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,-octadecahydro-2H-picen-3-one were present in the B. ferruginea fraction. Obviously, B. ferruginea is a reservoir to many pentacyclic triterpenoids. The pentacyclic triterpenoids may be used as a biomarker in the chemo taxonomical classification of the plants whilst acting as relevant contributors to the acclaimed biological benefits of B. ferruginea reported in traditional medical practices . The leaves of the two plants contain many bioactive compounds which may find application in pharmaceutical formulations as well as nutraceuticals and bio-pesticides preparations
Keywords : chromatography, fatty acid esters, fractions, friedelan 3 one, metabolites