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  • Selcuk Journal of Agriculture and Food Sciences
  • Volume:18 Issue:34
  • Injecting The Prepubertal Laboratory Mice with A Mixture af Serine and Threonine and Its Effect on S...

Injecting The Prepubertal Laboratory Mice with A Mixture af Serine and Threonine and Its Effect on Spermatogenic Function

Authors : Hüseyin Baki ÇİFTÇİ
Pages : 41-45
View : 22 | Download : 22
Publication Date : 2004-12-25
Article Type : Research Paper
Abstract :The aim of this study is to determine the effect of injecting a mixture of Serine and Threonine on spermatogenic function within testes of prepubertal mice insert ignore into journalissuearticles values(QS strain);. Therefore, the mice were injected with Saline insert ignore into journalissuearticles values(Control); or a mixture of Serine and Threonine insert ignore into journalissuearticles values(Test); for 5 days. Following the last injection, the testes were removed and dehydrated then stained with PAS insert ignore into journalissuearticles values(Peri-odic Acid Schiff);. The diameter of tubules, diameter of Leydig cells and the numbers of round spermatids were measured on sections of the testes. The number of stage round spermatids was decreased by Serine and Threonine injection insert ignore into journalissuearticles values(P<0.05);. The total numbers of round spermatids per testis for control and test groups were detected as 1.660.32 and 1.060.05 insert ignore into journalissuearticles values(x106/mm3); respectively. This experiment shows that Serine and Threonine injection reduced the number of round spermatids while the diameters of Leydig cells and the diameters of tubules were not affected. The reason for reduced number of round spermatids might be a result of increased expression of TGF-s which might increase the apoptosis of the spermatogonia and this probably resulted with the reduction in the number of round spermatids.
Keywords : Fare, serine, threonine, spermatogenik fonksiyon

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