Evaluation of plasma catestatin levels in patient with coronary slow flow

Authors : Dursun TOPAL, Bedrettin BOYRAZ, Alkame AKGÜMÜŞ, Tezcan PEKER, Mustafa YILMAZ, Fahriye VATANSEVER AĞCA, Selçuk KANAT, Ömür AYDIN, Burhan ASLAN

Pages : 522-528

Doi:10.18621/eurj.372631

View : 23 | Download : 16

Publication Date : 2019-05-04

Article Type : Research Paper

Abstract : Objectives:  Coronary slow flow insert ignore into journalissuearticles values(CSF); is characterized by delayed opasification of the coronary arteries in the absence of obstructive coronary disease. Catestatin has several cardiovasculer actions, in addition to diminihed sympato-adrenal flow. The study was to investigated associations between CSF and plasma catestatin levels. Method:. This study included 45 CSF patients insert ignore into journalissuearticles values(37 male, mean age 48 ± 9.5 years); and 30 control individuals insert ignore into journalissuearticles values(24 male, mean age 48.4 ± 9 years);. Coronary flow was quantified according to the TIMI insert ignore into journalissuearticles values(Thrombolysis in Myocardial Infarction); frame count method for coronary arteries. Serum catestatin levels taken from blood samples were measured by ELISA method. These parameters were compared between the groups . Results:   When compared with to the control group the serum catestatin levels was found higher in the CSF group. In addition to this, mean platelet volume was also significantly higher in patients with coronary slow flow. Conclusions:  Our study revealed that catestatin levels are increased in patients with CSF. Coronary slow flow that increased catecholaminergic sympathetic system activities seem to be among the reasons of endothelial dysfunction. 
Keywords : catestatin, coronary slow flow, coronary artery disease