The efficacy of bleb needling revision with 5-fluorouracil in encapsulated bleb after unsuccessful trabeculectomy

Authors : Mehmet OKKA, Enver MİRZA, Refik OLTULU, Selman BELVİRANLI, Mehmet Kemal GÜNDÜZ

Pages : 990-995

Doi:10.18621/eurj.425740

View : 11 | Download : 9

Publication Date : 2019-11-04

Article Type : Research Paper

Abstract :Objectives: To investigate the efficacy of the bleb needling revision insert ignore into journalissuearticles values(BNR); procedure with the adjunctive use of 5-Fluorouracil insert ignore into journalissuearticles values(5-FU); in encapsulated bleb after unsuccessful trabeculectomy. Methods: We reviewed 16 eyes of 15 subjects who underwent BNR procedure due to encapsulated bleb after unsuccessful trabeculectomy. Demographic data, type of glaucoma, intraocular pressure insert ignore into journalissuearticles values(IOP); values of pre-BNR, IOP values of post-BNR at first day, first week and first month, follow up time and complications were recorded from patients’ files, retrospectively . Results: The mean follow up time was 53.1 ± 26.4 weeks. The average time between previous unsuccessful trabeculectomy and BNR was 11.12 ± 8.79 weeks. The mean IOP of pre-BNR was 26.0  ± 4.4 mmHg and significantly decreased to 12.4 ± 5.0 mmHg post-BNR at the first day insert ignore into journalissuearticles values( p < 0.001);. The mean IOP values of post-BNR at the first week was 13.3 ± 4.9 mmHg and at the first month was 14.8 ± 4.8 mmHg. According to the mean IOP of pre-BNR, the mean IOP values of post-BNR at the first week and at the first month were significantly lower insert ignore into journalissuearticles values( p < 0.001 and p < 0.001, respectively);. Seven insert ignore into journalissuearticles values(44%); eyes were achieved success and eight insert ignore into journalissuearticles values(50%); eyes were achieved qualified success. One insert ignore into journalissuearticles values(6%); eye was classified as the failure. Conclusion: The bleb needling revision procedure with the adjunctive use of 5-FU in encapsulated bleb after unsuccessful trabeculectomy is a simple, useful and repeatable method to restore the dysfunctional bleb. 
Keywords : Bleb needling revision, 5 Fluorouracil, encapsulated bleb, trabeculectomy, filtration surgery