Fragmented QRS formation may be associated with increased carotid intima-media thickness in patients with end-stage renal disease

Authors : Tolga DOĞAN, Mucahit YETİM, İbrahim DOĞAN, Macit KALÇIK, Lütfü BEKAR, Oguzhan CELIK, Yusuf KARAVELİOĞLU

Pages : 481-487

Doi:10.18621/eurj.939697

View : 22 | Download : 12

Publication Date : 2021-09-04

Article Type : Research Paper

Abstract :Objectives: The aim of this study was to evaluate the relationship between carotid intima-media thickness and the presence of fragmented QRS in end-stage renal disease patients. Methods: The study included 100 end-stage renal disease patients who received hemodialysis treatment. Two groups were formed according to the presence of electrocardiography and fragmented QRS: the fragmented QRS insert ignore into journalissuearticles values(+); insert ignore into journalissuearticles values(Group I); and the fragmented QRS insert ignore into journalissuearticles values(-); insert ignore into journalissuearticles values(Group II);. Echocardiographic measurements of the cardiac dimensions and carotid intima-media thickness were examined. Results: The study population included 41 end-stage renal disease patients with fragmented QRS insert ignore into journalissuearticles values(48.8% male); and a control group of 59 end-stage renal disease patients without fragmented QRS insert ignore into journalissuearticles values(35.6% male); on electrocardiography. Left ventricular end systolic diameters insert ignore into journalissuearticles values( p = 0.012);,left ventricular end diastolic diameters insert ignore into journalissuearticles values( p < 0.001);, left atrial diameter insert ignore into journalissuearticles values( p = 0.001);, interventricular septal thickness insert ignore into journalissuearticles values( p < 0.001);, posterior wall thickness insert ignore into journalissuearticles values( p < 0.001); and left ventricular hypertrophy insert ignore into journalissuearticles values( p < 0.001);, blood urea nitrogen insert ignore into journalissuearticles values( p = 0.011);, creatinine insert ignore into journalissuearticles values( p = 0.014);, uric acid insert ignore into journalissuearticles values( p < 0.05); and parathyroid hormone insert ignore into journalissuearticles values( p < 0.05); values were found to be significantly increased in the fragmented QRS insert ignore into journalissuearticles values(+); group. The right and left carotid intima-media thickness values were significantly higher in fragmented QRS insert ignore into journalissuearticles values(+); patients than fragmented QRS insert ignore into journalissuearticles values(-); patients insert ignore into journalissuearticles values(right:[0.81 ± 0.19] vs [0.62 ± 0.14] mm, p < 0.001); and left: [0.83 ± 0.19 vs 64 ± 0.14], p < 0.001; respectively);. Conclusions: In end-stage renal disease patients, the presence of fragmented QRS, left ventricular hypertrophy and increased carotid intima-media thickness are important markers in the evaluation of the inflammatory process of atherosclerosis.
Keywords : fQRS, Carotid Intima Media Thickness, End Stage Renal Disease, left ventricular hypertrophy