The Effect of Acupuncture and Diet on Serum Leptin and Nesfatin-1 Levels in Overweight/Obese Individuals

Authors : Tevhid AYDIN, Ruhuşen KUTLU, Hayriye BALTAOĞLU ALP, İbrahim KILINC

Pages : 370-380

Doi:10.21763/tjfmpc.1270587

View : 50 | Download : 77

Publication Date : 2023-09-20

Article Type : Research Paper

Abstract :Acupuncture applications and diet are frequently used in obesity treatment. We aimed to investigate the changes in serum leptin and nesfatin-1 levels measured before and after acupuncture and diet in overweight/obese individuals in the presented study. This interventional study was carried out on 90 overweight/obese patients. Participants were divided into three groups: Group 1 insert ignore into journalissuearticles values(Acupuncture);, Group 2 insert ignore into journalissuearticles values(Diet);, and Group 3 insert ignore into journalissuearticles values(Those who did not take any attempts to lose weight- control group);. Serum leptin and nesfatin-1 levels were measured before and after the intervention. The 30th days leptin values were significantly decreased in the acupuncture group insert ignore into journalissuearticles values(p=0.040); while they were significantly increased in the control group insert ignore into journalissuearticles values(p=0.039);. It was detected that the nesfatin-1 values were significantly increased in both acupuncture insert ignore into journalissuearticles values(p=0.032); and diet groups insert ignore into journalissuearticles values(p=0.017);. Also, body weights significantly decreased both in acupuncture insert ignore into journalissuearticles values(p=0.032); and diet groups insert ignore into journalissuearticles values(p<0.001);. Our results support the effects of acupuncture treatment on appetite hormones. Further research on the mechanisms of endogenous and exogenous actions of the recently discovered hormones, leptin and nesfatin-1, are needed.
Keywords : Akupunktur, Diyet, Leptin, Obezite, Nesfatin 1