Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients

Authors : Mehmet USTA, Alparslan ERSOY, Yavuz AYAR

Pages : 21-25

Doi:10.46310/tjim.632066

View : 23 | Download : 11

Publication Date : 2019-10-29

Article Type : Research Paper

Abstract :Abstract Aim:  This study investigated the effect of mycophenolate mofetil insert ignore into journalissuearticles values(MPA); treatment instead of azathioprine insert ignore into journalissuearticles values(AZA); on renal function after kidney transplantation.  Methods : Thirteen of all recipients were taking a cyclosporine-based regimen and serum creatinine levels were above 1.5 mg/dL. In 13 patients, MPA treatment was started instead of AZA. Renal functions were evaluated for 12 months after MPA treatment.  Results : Serum creatinine levels increased from 2.11±0.48 mg/dL to 2.16±0.72 mg/dL at 12th months. This increase was not statistically significant. Serum creatinine levels decreased in 5 of 13 patients.  Conclusion : In selected patients, conversion from AZA to MPA may slow down the rate of deterioration in graft functions.
Keywords : azathioprine, mycophenolate mofetil, kidney transplantation recipient