The relationship between coronary artery disease and hs-troponin T changing during exercise stress test

Authors : İsmail GÜRBAK, Musatafa Tarık AĞAÇ, Şükrü ÇELİK

Pages : 156-163

Doi:10.46310/tjim.875638

View : 40 | Download : 12

Publication Date : 2021-10-29

Article Type : Research Paper

Abstract :Background The aim of this study was to investigate the relationship between coronary artery disease and changing of high sensitivity troponin T insert ignore into journalissuearticles values(hs-TnT); values during exercise stress test insert ignore into journalissuearticles values(EST); in patients with suspected coronary artery disease. Material and Methods We included 68 patients who underwent coronary angiography after positive EST. The hs-TnT values of all patients were measured before EST and at 4 hours after EST. Patients with coronary artery stenosis of 50% or more were divided into two groups [CAD insert ignore into journalissuearticles values(+);] and those without [CAD insert ignore into journalissuearticles values(-);].hs-TnT values measured before and after EST were compared. Results Among the 68 patients evaluated, 26 patients insert ignore into journalissuearticles values(39.3%); were identified as CAD insert ignore into journalissuearticles values(-); and 42 patients insert ignore into journalissuearticles values(61.7); as CAD insert ignore into journalissuearticles values(+);.There was no significant difference between the two groups in the hs-TnT values before and after EST. There was a significant correlation between hs-TnT before exercise and pre-EST systolic blood pressure insert ignore into journalissuearticles values(SBP); insert ignore into journalissuearticles values(r = 0.313, p = 0.009); and hs-TnT before exercise and peak SBP during EST insert ignore into journalissuearticles values(r=0.241, p=0.038);, anda also we found a correlation between hs-TnT after EST and peak SBP during EST insert ignore into journalissuearticles values(r = 0.398, p = 0.001);. However, a strong negative correlation was found between the Duke treadmill score insert ignore into journalissuearticles values(DTS); calculated by the exercise test parameters and the Syntax score, which indicates the extent and severity of coronary artery disease insert ignore into journalissuearticles values(r =-0.521, p = 0.0001);. Conclusions As a result of our study, it was observed that hs-TnT values did not contribute to the diagnosis of coronary artery disease. However, DTS evaluation performed before invasive coronary angiography can provide important information about coronary artery lesion complexity.
Keywords : hs troponin T, exercise stress testing, coronary artery disease, syntax score

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