Effects of multimorbidity and polypharmacy on blood pressure target attainment in patients with hypertension

Authors : Alper Tuna Güven, Naciye Hocanın, Arif Emre Ambarkütükoğlu, Ceren Kaplan, Tuana Çaylayık, Yasemen Arzani Ardebili, Elif Özden, Sevcan Karasüleymanoğlu, Zülal Şahin

Pages : 128-134

Doi:10.46310/tjim.1482744

View : 45 | Download : 57

Publication Date : 2024-07-29

Article Type : Research Paper

Abstract :Background Hypertension prevalence increases with age, as well as polypharmacy and multimorbidity (P&M), which are the use of multiple medications and the presence of multiple chronic diseases, respectively. Whether P&M affects attaining blood pressure (BP) goals is not clear. Methods Hypertensive patients in the general internal medicine outpatient clinic were evaluated retrospectively. Data regarding age, gender, comorbidities, medications, office BP (OBP), home BP (HBP), and ambulatory BP (ABP) were obtained. Having two or more diseases was classified as multimorbidity, whereas using five or more drugs was classified as polypharmacy. OBP 0.05), diastolic BP was lower in patients with both (all p 0.05). Conclusion P&M does not affect the achievement of office and home BP targets. Lower diastolic BP with P&M does not reflect better control but reflects the effect of age on diastolic BP.
Keywords : multimorbidity, polypharmacy, hypertension