Effects of The Peak to Baseline Ratio on Phase Difference of The Coupled Hodgkin Huxley Neurons

Authors : Hasan ESKALEN, Şükrü ÖZĞAN

Pages : 32-39

View : 21 | Download : 9

Publication Date : 2017-12-19

Article Type : Research Paper

Abstract :Phase response curve insert ignore into journalissuearticles values(PRC); examines how weak perturbation effects spike time of neurons. Peak-to- baseline ratio is one of the most important specification of type II PRC neurons a nd it gives a brief explanation  of PRC in terms of numerical sense. In this study, Hodgkin Huxley insert ignore into journalissuearticles values(HH); model neurons coupled via gap junction  under three different applied currents were investigated in terms of PRCs , peak-to-baseline ratio and required time  interval of minimum phase difference. Although the used three HH model neurons had same type of excitability  and PRCs, the shapes and maximum and minimum peaks were varied. The close relationship between peak- to-baseline  ratio and the required time interval of minimum phase difference of coupled neurons were found. To sum  up, the results of our simulations indicated that the required time of minimum phase differences of two coupled HH  neurons via gap junction were related to calculated peak-to-baseline ratios.
Keywords : Peak to baseline ratio, PRC, HH Model, phase difference