Barbaloin Attenuates Oxidative Testicular Injury Induced by Ischemia Reperfusion via Antioxidant Effects

Authors : Ömer TOPDAĞI, Ayhan TANYELİ, Fazile EKİNCİ, Ersen ERASLAN, Mustafa Can GÜLER

Pages : 28-33

View : 17 | Download : 9

Publication Date : 2020-03-30

Article Type : Research Paper

Abstract :The purpose of this research is to examine the protective effects of barbaloin on testis injury induced by ischemia reperfusion. In the experimental stage of our research, the rats were assigned to 4 groups. Our groups are scheduled as follows; sham, ischemia reperfusion, ischemia reperfusion + DMSO and ischemia reperfusion+barbaloin. Some oxidant, antioxidant and inflammatory parameters were evaluated in testis tissues obtained at the end of the experiment. In ischemia reperfusion group it was found out that the oxidant parameters increased and antioxidant parameters decreased but on the contrary, the antioxidant parameters increased and oxidant parameters decreased in the treatment group. These results demonstrated that barbaloin administration performed a protective effect against oxidative testis injury induced by ischemia reperfusion.
Keywords : ischemia reperfusion, barbaloin, testis, oxidative stress, inflamation