Preparation of cobalt oxide/gold nanoparticle modified glassy carbon electrode for electrochemical detection of dopamine

Authors : Ceren KUŞCU, Volkan ÖZDOKUR, Süleyman KOÇAK, Fatma Nil ERTAS

Pages : 15-21

View : 18 | Download : 7

Publication Date : 2020-06-23

Article Type : Research Paper

Abstract :This study deals with electrochemical preparation of cobalt oxide modified glassy carbon electrodes decorated with gold nanoparticles as an effective platform for dopamine insert ignore into journalissuearticles values(DA); detection. The experimental parameters affecting the oxidation signal of DA by square wave voltammetry have been evaluated. Under optimal conditions, developed sensor exhibited a linear response towards to DA in the concentration range of 6.0 10−8 to 7.5 10−6 M. The detection and quantification limits were calculated as 2.0 10−8 and 6.0 10−8M, respectively. The repeatability and reproducibility of the electrode were calculated as 13.2 and 16.1 % for 6.5 10-7 M insert ignore into journalissuearticles values(N = 3);, respectively. Finally, the sensor was successfully applied for the DA analysis in artificial cerebrospinal fluid, and the mean recovery was found as 105.8 ±6.5 % by standard addition method.
Keywords : Dopamine, square wave voltammetry, cobalt oxide