Improvement of in vitro antimicrobial and antifungal activities of peppermint essential oil conjugated with chitosan and promising antiviral properties

Authors : Pınar ŞEN, Parisa BOLOURİ, Fikrettin ŞAHİN

Pages : 77-82

Doi:10.51435/turkjac.1311200

View : 90 | Download : 48

Publication Date : 2023-06-30

Article Type : Research Paper

Abstract :The emergence of antimicrobial resistance has necessitate the new approaches. The peppermint insert ignore into journalissuearticles values(Mentha piperita L.); insert ignore into journalissuearticles values(PEO); oil is known for its antimicrobial and antifungal activities. However, the employing of it in practial applications is troublesome because of the sensitivity to the environmental conditions. Thus, it was immolized into chitosan to eliminate the difficulties in its use and increase its activity. It was observed that the immobilization of the PEO into the chitosan insert ignore into journalissuearticles values(PEO@Chitosan); influenced the biological activities resulting in less minimum Minimum Inhibitory Concentration insert ignore into journalissuearticles values(MIC); values in addition to protecting the essential oil by the chitosan as environment-friendly biomaterial. The determined MIC values of the target product insert ignore into journalissuearticles values(PEO@Chitosan); are between 0.001-0.95 mg/mL for the studied bacterial strains and 0.006-0.36 mg/mL for the studied fungi isolates, which led us to consider them as new therapeutic alternative. In vitro antiviral studies gave us that even if the encapsulation of the essential oil into the chitosan made the prepared product still promising as acandidate for the antiviral therapy treatment.
Keywords : Mentha piperita L, encapsulation, chitosan, antibacterial, antifungal and antiviral activity

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