Healing and Antimicrobial Effects of Olea europaea L (Memecik olive oil) on Wounds in Rats

Authors : Osman Bulut, Özgür Ecer, Ayşe Nur Akkoç, Semiha Yalçın

Pages : 9-15

Doi:10.53913/aduveterinary.1380203

View : 65 | Download : 63

Publication Date : 2024-06-28

Article Type : Research Paper

Abstract :This study evaluated the effectiveness of Olea europaea L. (Memecik olive oil) on wound healing in rats. A total of 63 Wistar albino rats were used to create a skin wound model. The study consisted of three groups: the control group, the olive oil group, and the positive control group (medication group). The results of the study revealed that the olive oil group exhibited faster wound healing, smaller wound areas, and a higher percentage of wound healing compared to the control and medication groups. Histopathological examination demonstrated a significant increase in epithelial tissue formation in the animals treated with olive oil. The presence of antimicrobial and antioxidant properties in olive oil may contribute to its positive effects on wound healing. The study also found that bacterial colonization increased on the second day in all groups, with the highest increase observed in the control group. However, by the 12th day, bacterial counts were found to be below the initial levels in both the olive oil and medication groups, except for the control group where it remained high. It is believed that the bacterial inhibitory effect observed in the group treated with olive oil is attributed to the phenolic compounds present in olive oil.
Keywords : Bakteri, epitelizasyon, granulasyon, inflamasyon

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