Plasma Nesfatin-1 Levels and its Relationship with Anxiety Levels in Obesity Diagnosed Population: A Controlled Study

Authors : Hayriye BAYKAN, Ozgur BAYKAN, Onur DURMAZ, Oguz Elif GULSAH, Hayrettin KARA, Serap AKDENİZ GORGULU, Ali YAMAN, Tunay KARLİDERE

Pages : 107-111

Doi:10.33808/clinexphealthsci.566075

View : 26 | Download : 15

Publication Date : 2019-06-30

Article Type : Research Paper

Abstract :Objective: Nesfatin-1 is a satiety neuropeptide involved in the regulation of metabolic pathways and food intake. Some studies have shown nesfatin-1 to be also associated with stress responses and stress-related behaviors. In the present study, we evaluated nesfatin-1 levels in obese individuals and investigated whether nesfatin-1 levels could be associated with anxiety levels in obese populations. Methods: Fifty-eight obese insert ignore into journalissuearticles values(29 anxious and 29 non-anxious); patients and 25 healthy control subjects between 18 and 65 years old were enrolled in the study. Plasma nesfatin-1 levels were measured with a commercial enzyme-linked immunosorbent assay, and anxiety levels were measured using the Hospital Anxiety and Depression Scale. Results: Plasma nesfatin-1 levels were significantly lower in both obese and anxious subjects and obese and non-anxious subjects than in the control group. No significant differences were found between the obese+anxious group and the obese+nonanxious group. Conclusion: Our results suggest that plasma nesfatin-1 levels are decreased and not associated with anxiety levels in obese populations 
Keywords : Nesfatin 1, Obesity, Anxiety