Efficacy of Hyaluronic Acid Gel as an Adjunct to Non-Surgical Periodontal Treatment in Smokers with Periodontitis: A Retrospective Case Control Study

Authors : Hafize ÖZTÜRK ÖZENER, Ömer Birkan AĞRALI, Hatice Selin YILDIRIM

Pages : 172-177

Doi:10.33808/clinexphealthsci.709327

View : 28 | Download : 9

Publication Date : 2020-06-29

Article Type : Research Paper

Abstract :Objective: To investigate the clinical effectiveness of adjunctive hyaluronic acid insert ignore into journalissuearticles values(HA); application to non-surgical periodontal treatment insert ignore into journalissuearticles values(NSPT); on periodontal parameters and gingival crevicular fluid insert ignore into journalissuearticles values(GCF); volume in smoking patients with stage III and grade C periodontitis. Methods: Records of patients who underwent previously NSPT with or without HA gel application were reviewed. The clinical examinations and radiographs of patients, which were collected, are used as data. At baseline, 1 and 3 months, periodontal parameters such as plaque index insert ignore into journalissuearticles values(PI);, gingival index insert ignore into journalissuearticles values(GI);, bleeding on probing insert ignore into journalissuearticles values(BOP);, probing depth insert ignore into journalissuearticles values(PD); and clinical attachment level insert ignore into journalissuearticles values(CAL);, and GCF volume were assessed. Results: Total 20 patients insert ignore into journalissuearticles values(male/female: 15/5); were included in the study who met the eligibility criteria. For 10 of these patients only NSPT was performed insert ignore into journalissuearticles values(Control group);, the other 10 patients received NSPT with HA gel application insert ignore into journalissuearticles values(Test group);. Intra‐group differences in both groups were significant in periodontal parameters: PI insert ignore into journalissuearticles values(both, p<0.001);, GI insert ignore into journalissuearticles values(both, p<0.001);, BOP insert ignore into journalissuearticles values(both, p<0.001);, PD insert ignore into journalissuearticles values(both, p<0.05); and CAL insert ignore into journalissuearticles values(both, p<0.05);; and in GCF volume insert ignore into journalissuearticles values(both, p<0.05);. No statistically significant differences were determined between the treatment groups at any assessment time periods in any outcomes insert ignore into journalissuearticles values(all, p>0.05); nor in the changes insert ignore into journalissuearticles values(∆); with time insert ignore into journalissuearticles values(all, p>0.05);. Conclusion: Compared to NSPT alone, the application of HA as adjunct to NSPT did not have any additional clinical effectiveness in smokers having periodontitis.
Keywords : Gingival Crevicular Fluid, Hyaluronic Acid, Periodontitis, Root planing