SYNTHESIS OF CERTAIN 4-METHYL-2-THIOURACIL DERIVATIVES TO BE TESTED AS ANTI-TUMOR OR ANTI-THYROID AGENTS

Authors : Rm ABDELRAHMAN

Pages : 0-0

Doi:10.1501/Commub_0000000249

View : 36 | Download : 18

Publication Date : 1985-01-01

Article Type : Research Paper

Abstract :Uracil and its 5-methyl derivative; thymine, are biologically öf great importance in fundamental metabolism. They derive their importance because certain of their derivatives are building blocks of RNA and DNA., 5-Fluorouıacil is particularly effective in the treatment of advan- ced carcinoma especially of the breast and the gastrointestinal tract; thiouracil, used in treating hyperthyroidism and angina pectoris.
Keywords : SYNTHESIS, THIOURACIL DERIVATIVES, ANTI TUMOR

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