ANTIMUTAGENIC AND ANTIOXIDANT ACTIVITIES OF TEUCRIUM MULTICAULE AND ITS CYTOTOXIC EFFECT ON MURINE LR7 CELL

Authors : Mustafa PEHLİVAN, Önder YUMRUTAŞ, İbrahim BOZGEYİK

Pages : 95-104

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Publication Date : 2020-06-30

Article Type : Research Paper

Abstract :In present study, DNA protection, antioxidant and cytotoxic effects of Teucrium multicaule Montbret Et Aucher Ex Bentham methanol extract insert ignore into journalissuearticles values(TME); was investigated. Cytotoxic effects and antioxidant activities of TME was determined by MTT and DPPH scavenging and DNA protection methods. As a result, high dose of TME exhibited a cytotoxic effect on murine L cells. Although, TME also showed a strong antimutagenic activity in DNA protection test system, it exhibited modest activity in DPPH test system. Consequently, it may be used as natural agent for antioxidant and antimutagenic properties.
Keywords : Cytotoxicity, DNA protection, Antioxidant, Antimutagenic, Teucrium multicaule