Investigation of antioxidant, enzyme inhibitory effects and total secondary metabolite quantification of Ornithogalum nutans L. methanol

Authors : Mehmet Özgür Atay, Gülsüm Cengaver, Yağmur Güzel, Ramazan Mammadov

Pages : 305-315

Doi:10.25092/baunfbed.1242438

View : 56 | Download : 34

Publication Date : 2024-01-19

Article Type : Research Paper

Abstract :This study was designed to determine the antioxidant and enzyme inhibitory activities of methanol extracts of different parts (aerial and bulb) of Ornithogalum nutans as well as to investigate the total phenolic and flavonoid amounts. While the total phenolic content of the extracts varied between 1.43±0.01/3.05±0.04 mg GAE/g of extract equivalent, the total flavonoid amount varied between 0.33±0.01/1.79±0.02 mg QE/g. Antioxidant activities were determined by DPPH, ABTS, ß-Carotene/Linoleic acid, CUPRAC, and FRAP methods. The antioxidant activity studies determined that the aerial methanol extract exhibited a higher activity than the bulb. Acetylcholinesterase and tyrosinase enzyme inhibitory activities of the extracts were determined, and the extracts showed lower activity than galantamine (89.41±0.05 %) and kojic acid (89.41±0.05 %) used as standard. The results reveal the potential of O. nutans extracts to be used in pharmacological studies in the pharmaceutical and food industries.
Keywords : Ornithogalum nutans, antioksidan, asetilkolinesteraz, tirozinaz, sekonder metabolit