Could Hemoglobin, Albumin, Lymphocyte and Platelet (HALP) score predict poor prognosis in patients with acute ischemic stroke?

Authors : İlkin İyigündoğdu, Güven Girgin, Zeynep Kaya, Eda Derle, Ülkü Sibel Benli
Pages : 165-171
Doi:10.30565/medalanya.1692942
View : 152 | Download : 342
Publication Date : 2025-12-31
Article Type : Research Paper
Abstract :Aim: HALP (Hemoglobin, Albumin, Lymphocyte and Platelet) score was shown to have an association with prognosis in malignancies. However, the relationship between HALP score and prognosis in ischemic stroke is not clear. This study aimed to evaluate the relationship between HALP score and functional outcomes at discharge in patients with acute ischemic stroke. Methods: A retrospective analysis was conducted on patients hospitalized with acute ischemic stroke. The HALP score was calculated. The functional status of the patients at discharge were assessed by the Modified Rankin Scale, and patients with mRS≥3 were considered to have a poor prognosis. The relationship between the HALP score, early functional results, and mortality rates of the patients was statistically evaluated. p< 0.05 was considered as significant. Results: After exclusion criteria, data of 159 patients were analyzed. The median HALP score was 41.68. At discharge, 57 patients (35.8%) had poor prognosis. The median HALP score was significantly lower in patients with poor prognosis compared to those with good prognosis (p<0.001). The HALP score was lower in patients with mortality than patients that survive (p<0.001). The optimal cut-off value for the HALP score to predict prognosis at discharge was 37.945. Conclusion: The HALP score may be valuable for predicting prognosis in patients with ischemic stroke. However, many variables of patients can affect prognosis. Therefore, it should be kept in mind that markers such as the HALP score should be evaluated together with other clinical parameters and the general condition of the patient.
Keywords : HALP skoru, prognoz, iskemik inme

ORIGINAL ARTICLE URL