Ganglion Cell Layer, Inner Plexiform Layer, and Choroidal Layer Correlate Better with Disorder Severity in ADHD Patients than Retinal Nerve Fiber Layer: An Optical Coherence Tomography Study

Authors : Mahmut Zabit KARA, Mehmet Hamdi ÖRÜM, Ayşe Sevgi KARADAĞ, Aysun KALENDEROĞLU

Pages : 578-82

Doi:10.37990/medr.1313614

View : 23 | Download : 42

Publication Date : 2023-09-18

Article Type : Research Paper

Abstract :Aim: To assess the thickness of the choroidal layer, inner plexiform layer insert ignore into journalissuearticles values(IPL);, ganglion cell layer insert ignore into journalissuearticles values(GCL);, and retinal nerve fiber layer insert ignore into journalissuearticles values(RNFL); in individuals with attention-deficit/hyperactivity disorder insert ignore into journalissuearticles values(ADHD);. Material and Methods: In this retrospective study, we used a spectral optical coherence tomography insert ignore into journalissuearticles values(OCT); device. The CPRS-48 was performed to the ADHD group. Results: Both groups consisted of 60 subjects. There were significant differences in NS segment of RNFL insert ignore into journalissuearticles values(right p=0.039; left p=0.035);. The mean right choroidal thickness of ADHD group was significantly lower than the control group insert ignore into journalissuearticles values(p=0.015);. The left GCL and IPL volumes of ADHD group were significantly lower than the control group insert ignore into journalissuearticles values(p<0.05);. In ADHD group, a significant correlation was found between right choroid and opposition insert ignore into journalissuearticles values(r=0.278, p<0.05); and conduct insert ignore into journalissuearticles values(r=0.373, p<0.01); subscales of CPRS-48; between age and right choroid insert ignore into journalissuearticles values(r=0.248, p<0.05);. In control group, a significant correlation was found between age and right NS insert ignore into journalissuearticles values(r=-0.370, p<0.05);, right TS insert ignore into journalissuearticles values(r=-0.381, p<0.05);, right mean RNFL insert ignore into journalissuearticles values(r=-0.352, p<0.05);, left NS insert ignore into journalissuearticles values(r=-0.397, p<0.05);, right choroid insert ignore into journalissuearticles values(r=0.422, p<0.01);, left choroid insert ignore into journalissuearticles values(r=0.443, p<0.01);, right GCL insert ignore into journalissuearticles values(r=0.425, p<0.01);, right IPL insert ignore into journalissuearticles values(r=0.446, p<0.01);. Conclusion: This study demonstrated that there is an association between disorder severity, duration of disorder, choroidal layer thickness, GCL, IPL and ADHD.
Keywords : Ganglion cell layer, inner plexiform layer, retinal nerve fiber layer, attention deficit hyperactivity disorder, optical coherence tomography