Evaluation of Children with Acute Pancreatitis

Authors : Burcu Ceylan CURA YAYLA, Ceyda TUNA KIRSAÇLIOĞLU, Tülin ŞAYLI

Pages : 137-143

View : 19 | Download : 5

Publication Date : 2019-12-10

Article Type : Conference Paper

Abstract :Although acute pancreatitis insert ignore into journalissuearticles values(AP); is uncommon in children, causes significant morbidity and mortality. This study aims to evaluate the clinical and laboratory findings, treatment approaches, complications of children with acute pancreatitis. Material and methods: Thirty children who were diagnosed as acute pancreatitis during January 2008-April 2013 were evaluated. Results: The most common etiology of acute pancreatitis was the drugs insert ignore into journalissuearticles values(30%);, particularly L- asparaginase insert ignore into journalissuearticles values(44.5%);. The biliary tract diseases insert ignore into journalissuearticles values(26.7%);, infection insert ignore into journalissuearticles values(16.7%);, hyperlipidemia insert ignore into journalissuearticles values(10%);, cystic fibrosis insert ignore into journalissuearticles values(3.3%);, and post-endoscopic retrograde cholangiopancreatography pancreatitis insert ignore into journalissuearticles values(3.3%); were other causes, and among 10%, no reason was detected. Abdominal pain insert ignore into journalissuearticles values(83,3%);, nausea insert ignore into journalissuearticles values(70%);, loss of appetite insert ignore into journalissuearticles values(63.3%);, vomiting insert ignore into journalissuearticles values(56.7%);, and fever insert ignore into journalissuearticles values(20%); were the most common symptoms. In 86.6% of cases amylase, in 73.9% lipase, and in 66.7% pancreatic amylase were elevated three times the upper limit of normal. The alanine transaminase, total and direct bilirubin levels in not drug-induced pancreatitis were higher than drug-induced pancreatitis insert ignore into journalissuearticles values(p<0.05);. Ultrasonography, abdominal tomography, magnetic resonance cholangiopancretography revealed pancreatitis related changes 63.3%, 85%, 70% of patients, respectively. Oral feeding was started on 4 ± 5.6 days, with polymeric diet insert ignore into journalissuearticles values(30%);, and medium chain triglyceride rich enteral diet insert ignore into journalissuearticles values(70%);. The length of hospitalization was 16.5 ± 15.1 days insert ignore into journalissuearticles values(4-66 days);. The patients fed with polymeric diet had a shorter hospitalization duration insert ignore into journalissuearticles values(p<0.05);. The delayed initiation of oral feeding caused longer LOH insert ignore into journalissuearticles values(p<0.001);. Pseudocyst insert ignore into journalissuearticles values(6,7%);, sepsis insert ignore into journalissuearticles values(6.7%);, and necrosis insert ignore into journalissuearticles values(3.3%); were the complications developed in patients. Conclusion: Consequently, this study underlines the children with acute abdominal pain, especially who use drugs like asparaginase and valproic acid, or that are known to have gallstone/biliary sludge, need to be examined for acute pancreatitis through pancreatic enzymes and ultrasonography. Moreover, the study also highlights that early feeding in acute pancreatitis is related with shorter hospitalization duration.
Keywords : Acute pancreatitis