Some Routine Laboratory Measurements And Antibiotic Choice As Potential Predictors of Mortality in The Pediatric İntensive Care Unit: A Cross-Sectional Study

Authors : Feyza İNCEKÖY GİRGİN

Pages : 305-313

View : 23 | Download : 7

Publication Date : 2019-12-10

Article Type : Conference Paper

Abstract :White blood cell insert ignore into journalissuearticles values(WBC);, platelet insert ignore into journalissuearticles values(PLT); count, and CRP are some basic parameters to follow the outcome of patients in intensive care units. This study aimed to evaluate the differences in the outcome of patients related to some routine laboratory measurements and antibiotic preferences. Methods: The participants of the study consisted of 179 pediatric ICU inpatients with gram-positive culture results. Hospital records covering the years 2016 to 2019 were reviewed. Other than the mortality status, data were collected on age, sex, the presence of fever, culture results, antibiotic preferences, and laboratory parameters such as WBC, PLT, and CRP levels. Results: The median insert ignore into journalissuearticles values(IQR); age of the patients was 33.00 insert ignore into journalissuearticles values(8.00-66.00); months; 109 insert ignore into journalissuearticles values(60.89%); were boys, while 70 insert ignore into journalissuearticles values(39.11%); were girls. Of the patients, 90 insert ignore into journalissuearticles values(50.3%); had positive culture results, 59 insert ignore into journalissuearticles values(33%); received vancomycin, 31 ‎insert ignore into journalissuearticles values(17.3%); received teicoplanin, and 34 insert ignore into journalissuearticles values(18.9%); had a fatal outcome.‎ The cultured organisms were as follows: Staph. spp. insert ignore into journalissuearticles values(n=56, 31.3%);, methicillin-resistant Staph. epidermidis insert ignore into journalissuearticles values(n=81, 45.3%);, Staph. aureus insert ignore into journalissuearticles values(n=22, 12.3%);, Staph. epidermidis insert ignore into journalissuearticles values(n=15, 8.4%);, and methicillin-resistant Staph. aureus insert ignore into journalissuearticles values(n=5, 2.8%);. WBC and PLT levels were higher in survived patients than the deceased ones insert ignore into journalissuearticles values(p=0.001 and p<0.001‎‎, respectively. There was no significant association of mortality and any of the studied categorical variables insert ignore into journalissuearticles values(p>0.05);.‎ Conclusion: CRP and PLT are useful indicators for the diagnosis of serious bacterial infections and the prediction of the clinical outcome. There is no difference between using vancomycin or teicoplanin concerning mortality in the ICU.
Keywords : WBC, platelet, CRP, pediatric intensive care unit