The Frequency of Pancreatic Enzyme Elevations and Effect on Disease Severity in COVID-19

Authors : Sevil ALKAN, Oruç Numan GÖKÇE, Havva Yasemin ÇİNPOLAT

Pages : 209-215

Doi:10.33631/sabd.1199161

View : 17 | Download : 9

Publication Date : 2023-05-10

Article Type : Research Paper

Abstract :Aim: In this study, we aimed to evaluate the frequency of pancreatic enzyme elevations in COVID-19-infected patients and to examine the effect on disease severity. Material and Methods: A total of 1249 patients who hospitalized with COVID-19 infection were included. The frequency of pancreatic enzyme elevations and the effect on disease severity in patients infected with COVID-19 were investigated. Results: The pancreatic enzyme elevations insert ignore into journalissuearticles values(amylase/lipase or both); were detected in 32 of 1249 patients insert ignore into journalissuearticles values(incidence 2.96%);. 32 cases with a mean age of 64.97±5.63 years were included in this study. 30 insert ignore into journalissuearticles values(93.75%); of the cases were men’s gender. 31 insert ignore into journalissuearticles values(96.87%); of them had elevated amylase levels, 26 insert ignore into journalissuearticles values(81.25%); had elevated lipase levels and 25 insert ignore into journalissuearticles values(78.12%); of them had elevated both amylase and lipase levels. Only 10 insert ignore into journalissuearticles values(31.25%); of them tested radiological for acute pancreatitis insert ignore into journalissuearticles values(AP); and there was no radiological finding compatible with AP in any of the limited numbers of abdominal computerized tomography scans performed. 18 insert ignore into journalissuearticles values(56.25%); of the patients were transferred to the intensive care unit due to clinical worsening and mortality developed in 13 insert ignore into journalissuearticles values(40.62%); patients. The mean age of the deceased cases was 66.4±6.6 years and there was no statistically significant difference between deceased and survived COVID-19 patients insert ignore into journalissuearticles values(>0.05);. Conclusion: The median lymphocyte count was lower, and the median AST, ALT, and lipase levels were higher in the deceased group. Perhaps close clinical follow-up of patients with pathological findings in these values and radiological imaging, if necessary, may be beneficial in the method of the disease. Keywords: COVID-19; disease severity; pancreatic enzyme elevations.
Keywords : COVID 19, pankreatik enzim artışları, hastalık şiddeti