Effects of Nigella sativa L. on Lipid Peroxidation and Reduced Glutathione Levels in Erythrocytes of Broiler Chickens

Authors : Yasin Tuluce, Halil Ozkol, Bunyamin Sogut, Ismail Celik

Pages : 95-99

View : 21 | Download : 8

Publication Date : 2013-08-13

Article Type : Research Paper

Abstract :We aimed to determine the effect of Nigella sativa L. on reduced glutathione insert ignore into journalissuearticles values(GSH); and lipid peroxidation insert ignore into journalissuearticles values(as malondialdehyde, MDA); in erythrocytes of broiler chickens. We used 100 Ross 308 chickens and they were equally divided into four groups namely control, 0.5 %, 1 % and 1.5 % containing Nigella sativa L. The control group received control broiler fattening feed whereas, the treatments groups were fed by the feed containing 0.5 %, 1 % and 1.5 % grinded Nigella sativa L. seeds for 6 weeks, respectively. Erythrocyte MDA levels were significantly lower in 0.5 % insert ignore into journalissuearticles values(p<0.002); and 1 % insert ignore into journalissuearticles values(p<0.005); of Nigella sativa L. groups than in control although GSH levels were significantly insert ignore into journalissuearticles values(p<0.005); higher in 0.5 % and 1 % of Nigella sativa L. groups. The 1.5 % of Nigella sativa L. did not induce on MDA and GSH levels in the animals. In conclusion, Nigella sativa L. caused protective effects on the oxidative stress-induced erythrocyte injury by inhibiting free radical production and regulation of GSH.
Keywords : Nigella sativa L, lipid peroxidation, antioxidants, broiler chicks