Characterization and Antibacterial Activity of Electrospun Polyethylene oxide/Chitosan Nanofibers

Authors : Hanan YUNUS, Emel Ceyhun SABIR, Halil İbrahim İÇOĞLU, Behzat YILDIRIM, Osman GÜLNAZ, Mehmet TOPALBEKİROĞLU

Pages : 1-8

Doi:10.32710/tekstilvekonfeksiyon.1030386

View : 26 | Download : 15

Publication Date : 2023-03-31

Article Type : Research Paper

Abstract :This study aims to characterize and evaluate polyethylene oxide insert ignore into journalissuearticles values(PEO); and chitosan insert ignore into journalissuearticles values(CS); nanofibers produced by electrospinning method. Electrospinning solutions were used at three different concentrations insert ignore into journalissuearticles values(1, 2, 3 wt%); with five different PEO/CS mixing ratios insert ignore into journalissuearticles values(30/70, 40/60, 50/50, 60/40, 100/0);. FESEM, XRD and FTIR tests were applied for characterization of the nanofibers. Antibacterial activity of the nanofibers against Staphylococcus aureus and Klebsiella pneumoniae microorganisms was investigated using disk diffusion method. While 1 wt% of concentration was not suitable to obtain regular nanofibers, the nanofibers were uniform and largely free of beads at the other ones insert ignore into journalissuearticles values(2, 3 wt%);. The average diameters of the nanofibers varied from 59 to 298 nm depending on the concentration and mixing ratio. Strong hydrogen bonds were formed between two polymers, while the crystal structure of PEO did not change significantly when mixed with chitosan. The PEO/CS nanofibers showed no resistance to the selected bacteria.
Keywords : Chitosan, polyethylene oxide, electrospinning, nanofibers, antibacterial activity