Evaluation of Inflammatory Biomarkers in Predicting Strangulation in Incarcerated Inguinal Hernias in Adult Patients Admitted to the Emergency Department; Cross-Sectional Study

Authors : Nafis Vural, Murat Duyan, Ali Sarıdaş, Elif Ertaş, Hasan Can Güven

Pages : 276-282

Doi:10.29058/mjwbs.1465537

View : 103 | Download : 124

Publication Date : 2024-12-30

Article Type : Research Paper

Abstract :Aim: It is very important to determine the diagnosis of strangulation quickly and with high accuracy in patients presenting with incarcerated hernia. Early diagnosis of strangulation reduces the rate of bowel resection. The objective of our study was to assess the effectiveness and consistency of recently established indices, namely neutrophil lymphocyte ratio (NLR), the systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune-inflammation value (PIV) in predicting the occurrence of strangulation in incarcerated hernias. Material and Methods: Our study included patients over the age of 18 who presented to the emergency department with abdominal pain between 01.01.2020 and 01.01.2023 and were diagnosed with incarcerated inguinal hernia according to the examination results. There were two groups of patients with strangulated inguinal hernia (SIH) and non-strangulated inguinal hernia (NSIH). Receiver Operating Characteristic (ROC) analysis was used to define the cut-off in diagnostic value values. Results: A total of 128 patients (39 SIH and 89 NSIH) were enrolled. Neutrophil lymphocyte ratio, There was determined to be acceptable diagnostic power for SIH detection using SII, SIRI, and PIV (AUC:0.738-0.765). Conclusion: Biomarkers such as SII, SIRI, PIV and NLR can be utilized for prediction SIH in incarcerated hernias.
Keywords : Pan-immün-inflamatuar değeri, inkarsere herni, nötrofil lenfosit oranı, strangule inguinal herni, sistemik immüninflamatuar indeks, sistemik inflamasyon yanıt indeksi

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