LC-MS/MS Analysis and Biological Activities of Methanol Extract from Sagina apetala Ard.

Authors : Rabia Nur ÜN

Pages : 231-235

Doi:10.18466/cbayarfbe.1264511

View : 50 | Download : 26

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :This is the first study on the investigation of phenolic compounds of methanol extract insert ignore into journalissuearticles values(ME); of Sagina apetala and examination of its cell-based antioxidant and antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. The determination of phenolic compounds of ME was performed by LC-MS/MS and 25 main compounds were identified. For the cell-based antioxidant activity of ME, Vero cell line insert ignore into journalissuearticles values(Cercopithecus aethiops kidney epithelial, Monolayer); was used as the model cell line and ME was showed 61.22% cell viability. ME, also showed insignificant antibacterial activity against both gram-positive and gram-negative bacteria. In conclusion, this study in the species provides the basic data for future studies for the species.
Keywords : Sagina apetala Ard, Phenolic compounds, Antioxidant activity, Antibacterial activity