Coffee Active Ingredient Loaded Biopolymer Nanoparticles: Synthesis and Characterization

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Celal Bayar Üniversitesi Fen Bilimleri Dergisi
Volume:20 Issue:2
Coffee Active Ingredient Loaded Biopolymer Nanoparticles: Synthesis and Characterization

Coffee Active Ingredient Loaded Biopolymer Nanoparticles: Synthesis and Characterization

Authors : Özge Vardar, Ayça Mehmetoğlu Al, Yeliz Yıldırım

Pages : 72-81

Doi:10.18466/cbayarfbe.1448091

View : 91 | Download : 61

Publication Date : 2024-06-28

Article Type : Research Paper

Abstract :Cafestol (CFS) is present in unfiltered coffee types and exhibits antidiabetic, anti-inflammatory and anticarcinogenic properties. The ionic gelation method was used to synthesise CFS-loaded chitosan (CS), and alginate (ALG) nanoparticles with high loading efficiency. The characterization, thermal properties and surface morphology of CFS-loaded biopolymer nanoparticles were carried out by FTIR, TGA and SEM, respectively. The encapsulation efficiency of the synthesised CFS-loaded biopolymer nanoparticles was found to be as 53% (CFS-loaded ALGNPs) and 92% (CFS-loaded CSNPs) by high-pressure liquid chromatography. The particle sizes determined using Malvern Zeta Sizer Ultra were 97 ± 4.04 (CFS-loaded CSNPs) and 81 ± 6.51 (CFS-loaded ALGNPs).
Keywords : Alginate, Cafestol, Chitosan, Drug Delivery Systems, Nanoparticle

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