Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test

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Cumhuriyet Üniversitesi Fen-Edebiyat Fakültesi Fen Bilimleri Dergisi
Volume:36 Issue:3
Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test

Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test

Authors : Tofigh TAHERKHANI, Rasool ASGHARI ZAKARIA, Mahboubeh TAHERKHANI

Pages : 1682-1687

View : 38 | Download : 11

Publication Date : 2015-05-13

Article Type : Review Paper

Abstract :Abstract. The aim of this study was to determine the mutagenic and anti-mutagenic properties of the essential oil of Jurinea leptoloba DC in vitro . The mutagenic and anti-mutagenic activities of the oil was evaluated using the Salmonella typhimurium tester strains TA98 and TA100, together with nitrofluorene for TA98 and sodium azide for TA100 without (-S9) metabolic activation, and 2-aminoantracene for TA98 and TA100 with metabolic (+S9) activation. The results obtained with S. typhimurium suggest that the oil of J. leptoloba can not be exploited as an anti-mutagenic agent with low adverse side effects.
Keywords : Jurinea leptoloba, Essential oil, Mutagenic, Anti mutagenic

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