Relationship of intima-media thickness with Gensini score that determines the severity of coronary artery disease

Authors : Bircan Alan, Salih Hattapoğlu, Abdurrahim Dusak, Adem Aktan

Pages : 501-505

Doi:10.5798/diclemedj.0921.2015.04.0616

View : 23 | Download : 10

Publication Date : 2016-01-08

Article Type : Research Paper

Abstract :Objective:  In this study we aimed to compare carotid intima-media thickness (CIMT) with Gensini score which objective evidence to demonstrate the severity of coronary artery disease. Methods:  The study included 76 CAD patients (41 men, 35 women, mean age 60.7±11.2 years, range: 42-83) We calculated the Gensini score and measured CIMT for each patient, CAD patients was separated into two groups: patients with mild atherosclerosis (Gensini score <25 points) and severe atherosclerosis (Gensini score ≥25 points). The CIMT values were compared to Gensini score (CAD severity). Results:  The severe atherosclerosis group had significantly higher CIMT values compared to the mild atherosclerosis group [(1.2±0.16 range: 0.90-1.50), (0.97±0.07 range: 0.90-1.10), p<0.01, respectively]. There was a significant correlation with CIMT and Gensini score, age, BMI, LDL cholesterol [(r= 0.365, p<0.01), (r=0.327, p=0.03), (r=-0.341, p<0.01), (r=0.385, p<0.01), respectively. Conclusion:  We found a significant association between CIMT and Gensini score which objective evidence to severity of CAD. As a non-invasive measurement CIMT can be used as an additional method in recognition of severe coronary artery disease Key words:  Carotid intima-media thickness, Gensini score, coronary artery disease, ultrasonography
Keywords : Karotis intima media kalınlığı, gensini skoru, koroner arter hastalığı, ultrasonografi