Relationship between Fib-4 score and nutritional status in patients with pulmonary hypertension

Authors : Serdar Söner, Mehmet Özbek

Pages : 219-226

Doi:10.5798/dicletip.1722822

View : 29 | Download : 36

Publication Date : 2025-06-20

Article Type : Research Paper

Abstract :Objective: Nutritional status has been associated with poor prognosis in many cardiovascular diseases. Recently, the Fib-4 index, which is a marker of liver cirrhosis risk, has also been investigated in cardiovascular diseases, and its association with poor prognosis has been shown. The goal of this study was to examine the connection between pulmonary hypertension patients\\\' Fib-4 scores and nutritional status. Methods: 216 individuals who received a pulmonary hypertension diagnosis at our hospital between January 1, 2023, and December 31, 2023, were included in the research. The patients were divided into two groups based on their nutritional status: those who were malnourished (51) and those who were not (162). Results: Laboratory findings indicated that malnourished patients had significantly lower hemoglobin levels (12.3 ± 2.3 vs. 13.5 ± 2, p=0.002), platelet counts (228 ± 88 vs. 267 ± 123, p=0.044), and albumin levels (3.1 ± 0.4 vs. 4.1 ± 0.4, p<0.001) compared to non-malnourished patients. There was a strong correlation between the FIB-4 index and measures of nutritional status and inflammation. Conclusions: Malnourished individuals with PAH had greater comorbidity burdens and higher liver fibrosis indices. According to our study\\\'s findings, individuals with pulmonary hypertension may benefit from nutritional and liver health evaluations as part of their care to enhance their quality of life and clinical results.
Keywords : Pulmonary hypertension, Fib-4 index, Controlling nutritional status, Prognostic nutritional index

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