Immunohistochemical Expression of Beclin1 and Lc3 in the Ovary and Oviduct during Early Pregnancy in Rats

Authors : Sema Uslu, Füsun Erhan Baycumendur, Elif Nur Taş Kepenek

Pages : 23-27

View : 51 | Download : 29

Publication Date : 2025-06-30

Article Type : Research Paper

Abstract :Proteins associated with autophagy are called (Autophagy related proteins) Atg proteins. Atg6 (Beclin 1) complex regulates autophagy at the molecular level and lyses cytosolic proteins, organelles and cytoplasmic components in the autophagosome during autophagy. LC3 is an autophagosomal marker. Monitoring autophagy-related processes is very important in understanding pregnancy metabolism. In this study, Beclin 1 and LC3 were immunohistochemically demonstrated in the ovary and oviduct on day 5 in the first pregnancy period. Accordingly, on the 5th day of pregnancy, it was determined that autophagy continued to increase in pregnancy with the immunohistochemical (+) of Beclin 1, LC3 in interstitial cells, germinative epithelium, follicle granulosa cells and theca interna/externa in the ovary and epithelial cells in the oviduct.
Keywords : Beclin 1, gebelik, lc3, otofaji, wistar albino rat

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