Determination of Antioxidant Effect of Walnut (Juglans regia L.) on Lung and Muscle Tissue

Authors : Bedia BATİ, İsmail ÇELİK, Abdullah TURAN

Pages : 29-39

View : 47 | Download : 11

Publication Date : 2019-04-30

Article Type : Research Paper

Abstract :This study was to investigate the antioxidant role of Juglans regia L. (walnut) against ethanol-induced oxidative stress in lung and muscle tissues. Female Albino 36 rats were divided into six groups and treated as follows: I (control), II (20% ethanol), III (10%walnut), IV (20% ethanol + 10%walnut), V (5% walnut) and VI (20% ethanol + 5% walnut). The rats were sacrificed after 50 days of administration and the tissues were analyzed after isolation. According to the results, it was found that the increased malondialdehyde (MDA) content owing to the alcohol-induced oxidative stress in both tissues decreased in the walnut treated tissues. In addition alcohol and alcohol + walnut treatment of nutritional supplemented rats changed catalase (CAT), glutathione peroxidase (GPx), glutathione S-transferase (GST) and superoxide dismutase (SOD) content and antioxidant defence system (ADS) components compared to control rats. As a result, ethanol has been shown to cause fluctuations in ADS components as a result of oxidative stress in rats and it can be said that walnut has a curative effect on the this complications caused by oxidative stress.
Keywords : Juglans regia L, Antioxidant defense system, Malondialdehyde

ORIGINAL ARTICLE URL