Effect of Sulfamerazine on Oxidative Stress of Rainbow Trout (Oncorhynchus mykiss, Walbaum, 1792)

Authors : M Enis YONAR, Seval YILMAZ, Naim SAGLAM

Pages : 22-30

View : 19 | Download : 24

Publication Date : 2023-06-19

Article Type : Research Paper

Abstract :The aim of this study was to investigate effects of sulfamerazine on oxidative stress of rainbow trout insert ignore into journalissuearticles values(Oncorhynchus mykiss);. The fish were divided into four groups. The first group was fed with diets containing no sulfamerazine; the second group was supplemented with sulfamerazine at 100 mg kg-1 for 21 days; the third group was treated with sulfamerazine at 200 mg kg-1 for 21 days; fourth group were supplemented with sulfamerazine at 400 kg-1 for 21days. Blood samples were taken to determine of the malondialdehyde insert ignore into journalissuearticles values(MDA); levels and catalase insert ignore into journalissuearticles values(CAT); activities from fish on the 3rd, 7th, 14th and 21st days of feeding. The levels of MDA were lower in the groups exposed to three different doses of sulfamerazine treatment than in the control group on day 3rd. MDA levels began to increase depending on time at group supplemented with sulfamerazine. MDA levels were found to be higher at fish exposed to 200 mg kg-1 dose than those observed in fish exposed to 100 and 400 mg kg-1 dose of sulfamerazine insert ignore into journalissuearticles values(P<0.05);. CAT activities increased in rainbow trout after application of three different doses of sulfamerazine on day 3rd of exposure, while they decreased after application of sulfamerazine on day 14th, 21st of exposure. CAT activities were found to be higher at fish exposed to 200 mg kg-1 dose of sulfamerazine than those observed in fish exposed to 100 and 400 mg kg-1 dose insert ignore into journalissuearticles values(P<0.05);. It was observed that oxidant-antioxidant status changed in rainbow trout after application of different doses of sulfamerazine
Keywords : katalaz, malondialdehit, gökkuşağı alabalığı, sulfamerazin