Synthesis, characterization and investigation of biological activities of Schiff base and its Ni(II) complex obtained from 2-Benzoylpyridine and 3-Hydroxy-2-naphthoic hydrazide

Authors : Murat Çınarlı

Pages : 364-376

Doi:10.18185/erzifbed.1425404

View : 57 | Download : 52

Publication Date : 2024-08-31

Article Type : Research Paper

Abstract :In this paper, a new aryl hydrazone and its Nickel (II) complex were synthesized from 2-benzoylpyridine and 3-Hydroxy-2-naphthoic hydrazide. The synthesized compounds were characterized by elemental analysis, UV Vis., IR, NMR spectral studies and mass spectra. The data indicate that the metal atom is coordinated by the two ligands and that the [NiL2] complex is octahedral. The ligand is coordinated through carbonyl-O, azomethine-N, and pyridyl-N atoms. When tested against various reference bacterial strains and clinical isolates, it was discovered that the antibacterial activity of the [NiL2] complex was more effective than the ligand.
Keywords : Aryl hydrazone, Metal Complexes, Antimicrobial Studies, NNO Donor